|Introductions, GTP Student Advising Committee, Choose Fall topic, How to choose and critique a paper.|
Fall 2014: Classic Papers
|10/15/14||Babette Hammerling||Meselson and Stahl (1958) The replication of DNA in Escherichiacoli. PNAS44: 671-682. [pdf]|
|10/22/14||Cynthia Hsu||Brenner, Jacob, and Meselson (1961) An unstable intermediate carrying information form genes to ribosomes for protein synthesis. Nature 190: 576-581. [pdf]|
|10/29/14||Fernando Martinez||Jackson, Symons and Berg (1972) Biochemical method for inserting new genetic information into DNA of Simian Virus 40: Circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coli. PNAS . [pdf]|
|11/5/14||Jaime Barea||Beadle, G.W. and Tatum, E.L. (1941) Genetic control of biochemical reactions in Neurospora. PNAS 27: 499-506. [pdf]|
|11/12/14||Prof. Nik Schork||
Responsible Conduct of Research: Managing Conflicts of Interest.
|11/19/14||Micah Manary||Sturetevant (1913) The linear arrangement of six sex-linked factors in Drosophila as shown by their mode of association. J. Exp. Zool. 14: 43-59.
journal [pdf] E.S.P. reprint [pdf]
|12/3/14||Gabriel Pratt||Needleman and Wunsch (1970) A general method applicable to the search for similarities in the amino acid sequence of two proteins. J. Mol. Biol. 43: 443-453. [pdf]|
|12/10/14||Eric Scott||Sanger et al. (1977) Nucleotide sequence of bacteriophage phiX174 DNA.Nature 265: 687-695. [pdf]|
|12/17/14||Naomi Searle||Hartwell, Culotti, and Reid. (1970) Genetic Control of the Cell-Division cycle in Yeast, I. Detection of Mutants. PNAS 66: 352-359. [pdf]|
|Winter Break||Selection of Winter topic.|
Winter 2015: Population Genetics
|1/7/15||Michael Yu||Huerta-Sánchez et al. (2014) Altitude adaptation in Tibetans casued by introgression of Denisovan-like DNA. Nature 512, 194–197.|
Schaub et al. (2012) Linking disease associations with regulatory information in the human genome (Method). Genome Research 22, 1748-1759.
|1/21/15||Victoria Corey||Tishkoff et al. (2001) Haplotype Diversity and Linkage Disequilibrium at Human G6PD: Recent Origin of Alleles That Confer Malarial Resistance.Science 293, 455-462.|
|1/28/15||Sophia Española||Gurdasani et al (2015) The African Genome Variation Project shapes medical genetics in Africa. Nature 517, 327-332.|
|2/4/15||Kevin Ross||Simons et al. (2014) The deleterious mutation load is insensitive to recent population history. Nature Genetics 46, 220-224.|
|2/11/15||Bernardo Lara||King et al. (2015) Mosaic structural variation in children with developmental disorders. Human Mol. Genet. [pdf ahead of print]|
Prof. Anthony Magit, MD, MPH
|Use of human subjects in genetics research.|
|2/25/15||Genevieve Ryan||Schubert et al. (2014) Prehistoric genomes reveal the genetic foundation and cost of horse domestication. PNAS 111, E5661–E5669.|
|3/4/15||Sam Stoner||Lamichhaney et al. (2015) Evolution of Darwin's finches and their beaks revealed by genome sequencing. Nature 518, 371-375.|
||Carbone et al. (2014) Gibbon genome and the fast karyotype evolution of small apes. Nature 513, 195-201.|
Spring 2015: Agricultural Genetics
|4/1/15||Lawrence Wong||Shaatiel et al. (2007) Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system. Plant Biotechnology Journal 5, 579-590.|
|4/8/15||Danny Antaki||Pelsy et al. (2015) Chromosome replacement and deletion lead to clonal polymorphism of berry color in grapevine. PLOS Genetics 11, e1005081.|
|4/15/15||Daniel Chen||Lyall et al. (2011) Suppression of Avian Influenza Transmission in Genetically Modified Chickens. Science 331, 223-226 .|
|4/22/15||Wilmer Del Cid||Zheng et al. (2015) Full crop protection from an insect pest by expression of long double-stranded RNAs in plastids. Science 347, 991-994.|
|4/29/15||Prof. Michael Kalichman||
Responsible Conduct of Research. What are appropriate safeguards and standards for environmental release of engineered orgnaisms and human germline interventions?
|5/6/15||Jennifer Kuo||Mandell et al. (2015) Biocontainment of genetically modified organisms by synthetic protein design. Nature 518, 55–60.|
||Nathan Jameson||Huang, X. et al. (2015) Genomic analysis of hybrid rice varieties reveals numerous superior alleles that contribute to heterosis. Nat. Commun. 6: 6258.|
|5/20/15||Terry Solomon||Simcic et al. (2015) Recovery of native genetic background in admixed populations using haplotypes, phenotypes, and pedigree information - using cika cattle as a case breed. PLoS One. 10, e0123253.|
||Jenhan Tao||Wang et al. (2014) Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew. Nature Biotech.32, 947–951.|
|6/3/15||Tina Wang||Kim et al. (2014) Genomic-scale exchange of mRNA between a parasitic plant and its hosts. Science 345, 808-811.|
Faculty: Bruce Hamilton (Program Director), Richard Kolodner (Associate Director), Faculty Mentors.