Topics 2014-2015
Date | Presenter | Paper |
10/8/14 |
Organizational meeting |
Introductions, GTP Student Advising Committee, Choose Fall topic, How to choose and critique a paper. |
Fall 2014: Classic Papers
Date | Presenter | Paper |
10/15/14 | Babette Hammerling | Meselson and Stahl (1958) The replication of DNA in Escherichiacoli. PNAS44: 671-682. [pdf] |
10/22/14 | Cynthia Hsu | Brenner, Jacob, and Meselson (1961) An unstable intermediate carrying information form genes to ribosomes for protein synthesis. Nature 190: 576-581. [pdf] |
10/29/14 | Fernando Martinez | Jackson, Symons and Berg (1972) Biochemical method for inserting new genetic information into DNA of Simian Virus 40: Circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coli. PNAS . [pdf] |
11/5/14 | Jaime Barea | Beadle, G.W. and Tatum, E.L. (1941) Genetic control of biochemical reactions in Neurospora. PNAS 27: 499-506. [pdf] |
11/12/14 | Prof. Nik Schork |
Responsible Conduct of Research: Managing Conflicts of Interest. |
11/19/14 | Micah Manary | Sturetevant (1913) The linear arrangement of six sex-linked factors in Drosophila as shown by their mode of association. J. Exp. Zool. 14: 43-59. journal [pdf] E.S.P. reprint [pdf] |
Thanksgiving | ||
12/3/14 | Gabriel Pratt | Needleman and Wunsch (1970) A general method applicable to the search for similarities in the amino acid sequence of two proteins. J. Mol. Biol. 43: 443-453. [pdf] |
12/10/14 | Eric Scott | Sanger et al. (1977) Nucleotide sequence of bacteriophage phiX174 DNA.Nature 265: 687-695. [pdf] |
12/17/14 | Naomi Searle | Hartwell, Culotti, and Reid. (1970) Genetic Control of the Cell-Division cycle in Yeast, I. Detection of Mutants. PNAS 66: 352-359. [pdf] |
Winter Break | Selection of Winter topic. |
Winter 2015: Population Genetics
Date | Presenter | Paper |
1/7/15 | Michael Yu | Huerta-Sánchez et al. (2014) Altitude adaptation in Tibetans casued by introgression of Denisovan-like DNA. Nature 512, 194–197. |
1/14/15 | Alexandra Buckley |
Schaub et al. (2012) Linking disease associations with regulatory information in the human genome (Method). Genome Research 22, 1748-1759. |
1/21/15 | Victoria Corey | Tishkoff et al. (2001) Haplotype Diversity and Linkage Disequilibrium at Human G6PD: Recent Origin of Alleles That Confer Malarial Resistance.Science 293, 455-462. |
1/28/15 | Sophia Española | Gurdasani et al (2015) The African Genome Variation Project shapes medical genetics in Africa. Nature 517, 327-332. |
2/4/15 | Kevin Ross | Simons et al. (2014) The deleterious mutation load is insensitive to recent population history. Nature Genetics 46, 220-224. |
2/11/15 | Bernardo Lara | King et al. (2015) Mosaic structural variation in children with developmental disorders. Human Mol. Genet. [pdf ahead of print] |
2/18/15 |
Prof. Anthony Magit, MD, MPH |
Use of human subjects in genetics research. |
2/25/15 | Genevieve Ryan | Schubert et al. (2014) Prehistoric genomes reveal the genetic foundation and cost of horse domestication. PNAS 111, E5661–E5669. |
3/4/15 | Sam Stoner | Lamichhaney et al. (2015) Evolution of Darwin's finches and their beaks revealed by genome sequencing. Nature 518, 371-375. |
3/11/15 |
|
Carbone et al. (2014) Gibbon genome and the fast karyotype evolution of small apes. Nature 513, 195-201. |
Spring Break |
Spring 2015: Agricultural Genetics
Date | Presenter | Paper |
4/1/15 | Lawrence Wong | Shaatiel et al. (2007) Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system. Plant Biotechnology Journal 5, 579-590. |
4/8/15 | Danny Antaki | Pelsy et al. (2015) Chromosome replacement and deletion lead to clonal polymorphism of berry color in grapevine. PLOS Genetics 11, e1005081. |
4/15/15 | Daniel Chen | Lyall et al. (2011) Suppression of Avian Influenza Transmission in Genetically Modified Chickens. Science 331, 223-226 . |
4/22/15 | Wilmer Del Cid | Zheng et al. (2015) Full crop protection from an insect pest by expression of long double-stranded RNAs in plastids. Science 347, 991-994. |
4/29/15 | Prof. Michael Kalichman |
Responsible Conduct of Research. What are appropriate safeguards and standards for environmental release of engineered orgnaisms and human germline interventions? Assigned Papers:
|
5/6/15 | Jennifer Kuo | Mandell et al. (2015) Biocontainment of genetically modified organisms by synthetic protein design. Nature 518, 55–60. |
5/13/15 |
Nathan Jameson | Huang, X. et al. (2015) Genomic analysis of hybrid rice varieties reveals numerous superior alleles that contribute to heterosis. Nat. Commun. 6: 6258. |
5/20/15 | Terry Solomon | Simcic et al. (2015) Recovery of native genetic background in admixed populations using haplotypes, phenotypes, and pedigree information - using cika cattle as a case breed. PLoS One. 10, e0123253. |
5/27/15 |
Jenhan Tao | Wang et al. (2014) Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew. Nature Biotech.32, 947–951. |
6/3/15 | Tina Wang | Kim et al. (2014) Genomic-scale exchange of mRNA between a parasitic plant and its hosts. Science 345, 808-811. |
Faculty: Bruce Hamilton (Program Director), Richard Kolodner (Associate Director), Faculty Mentors.