Topics 2006-2007
| Date | Presenter | Paper |
| 9/27/06 |
Organizational meeting |
Introductions, Choose Fall topic, How to choose and critique a paper. |
Fall 2006: Development and Stem Cells
| Date | Presenter | Paper |
| 10/4/06 | Lindsay Lewellyn | Lee et al. (2006) Brat Is a Miranda Cargo Protein that Promotes Neuronal Differentiation and Inhibits Neuroblast Self-Renewal Dev. Cell 10: 441-449. |
| 10/11/06 | Tony Essex | Yoo and Greenwald (2005) LIN-12/Notch activation leads to microRNA-mediated down-regulation of Vav in C. elegans.Science 310: 1330-1333. |
| 10/18/06 | Jason Goode | Sustar and Schubiger (2005) A transient cell cycle shift in Drosophila imaginal disc cells precedes multipotency. Cell120: 383-393. |
| 10/25/06 | Rany Salem | Lu et al. (2004) Gene regulation and DNA damage in the aging human brain. Nature 429: 883-891. |
| 11/1/06 | Carrie Louie | Sawamoto et al. (2006) New neurons follow the flow of cerebrospinal fluid in the adult brain. Science 311: 629-632. |
| 11/8/06 | Wendy Alcaraz | Cappello et al. (2006) The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface. Nat. Neurosci. 9: 1099 - 1107 |
| 11/15/06 | Dustin Wakeman | Kuwabara et al. (2004) A small modulatory dsRNA specifies the fate of adult neural stem cells. Cell 116: 779-793. |
| Thanksgiving | ||
| 11/29/06 | Jarrod Heck | Cohen et al. (2006) Opposing Activities Protect Against Age-Onset Proteotoxicity. Science 313: 1604-1610. |
| 12/6/06 | Natalie Kardos | Kawakami et al. (2006) Wnt/b-catenin signaling regulates vertebrate limb regeneration. Genes & Development in press. Supplemental data |
| Winter Break |
Winter 2007: Population Genetics
| Date | Presenter | Paper |
| 1/3/07 | Madeline Lancaster |
Olendorf et al. (2006) Frequency-dependent survival in natural guppy populations. Nature 441: 633-636. |
| 1/10/07 | Kelly Lagor (rescheduled) | Song et al. (2006) POL and PLL1 phosphatases are CLAVATA1 intermediates required for Arabidopsis shoot and floral stem cells. Development 133: 4691-4698. |
| 1/17/07 | Janine Low | Tishkoff et al. (2006) Convergent adaptation of human lactase persistence in Africa and Europe. Nature Genetics 39: 31 - 40. |
| 1/24/07 | Molly Bush | Spielman et al. (2007) Common genetic variants account for differences in gene expression among ethnic groups. Nature Genetics |
| 1/31/07 | Dan Clark | Murgia et al. (2006) Clonal Origin and Evolution of a Transmissible Cancer. Cell 126: 477-487. |
| 2/7/07 | Ali Torkamani | Ramachandran et al. (2005) Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa. PNAS 102: 15942-15947. |
| 2/14/07 | Dustin Wakeman | Anderson et al. (2006) Ice-age endurance: DNA evidence of a white spruce refugium in Alaska. PNAS 33: 12447–12450. |
| 2/21/07 | Rany Salem | Sladek et al. (2007) A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature (advance online publication 11 February 2007). |
| 2/28/07 | Jarrod Heck | Yoshiura et al. (2006) A SNP in the ABCC11 gene is the determinant of human earwax type. Nature Genetics 38: 324-330. |
| 3/7/07 |
Emily Davis |
The Autism Genome Project Consortium (2007) Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nature Genetics 39: 319-328. |
Spring 2007: Behavioral Genetics
| Date | Presenter | Paper |
| 3/14/07 | Natalie Kardos | Kim et al. (2006) A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder. PNAS 103: 19164-19169. |
| 3/21/07 | Kelly Lagor |
Riley et al. (2006) Alcohol dependence is associated with the ZNF699 gene, a human locus related to Drosophila hangover, in the Irish affected sib pair study of alcohol dependence (IASPSAD) sample. Mol. Psychiatry 11: 1025–1031 Scholz et al. (2005) The hangover gene defines a stress pathway required for ethanol tolerance development. Nature436: 845-847. |
| Spring Break | ||
| 4/4/07 | Madeline Lancaster | Clutton-Brock et al. (2006) Intrasexual competition and sexual selection in cooperative mammals. Nature 444: 1065-1068. |
| 4/11/07 | Janine Low | Dorus et al. (2004) Rate of molecular evolution of the seminal protein gene SEMG2 correlates with levels of female promiscuity. Nature Genetics 36: 1326-1329. |
| 4/18/07 | Molly Bush | Roybal et al. (2007) Mania-like behavior induced by disruption of CLOCK. PNAS 104: 6406-6411. |
| 4/25/07 | Dan Clark | Conti et al. (2007) Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy, sleep deprivation and fluoxetine. Mol. Psychiatry 12: 167–189. |
| 5/2/07 | Ohn Chow | Winslow et al. (1993) A role for central vasopressin in pair bonding in monogamous prarie voles. Nature 365: 545-548. |
| 5/9/07 | Lindsay Lewellyn | Research talk |
| 5/16/07 | Tony Essex | Research talk |
| 5/23/07 | Jason Goode | Research talk |
| 5/30/07 | Rany Salem | Research talk |
| 6/6/07 | Carrie Louie | Research talk |
| 6/13/07 | Wendy Alcaraz | Research talk |
Faculty: Bruce Hamilton (Course Director), Anthony Wynshaw-Boris (Director, Genetics Training Grant)