Journal Club

Fall 2017 - Circadian Rhythms and Sleep

October 4: Organizational Meeting
Introductions, GTP advising committee, how to critique a paper, selection of Fall topic.

October 11: Overview– Emily Wheeler, Yeo Lab
Review: Takahashi (2016) Transcriptional architecture of the mammalian clock. Nat Rev Gent. 18: 164-179. [NRG]

October 11: Michael Baughn, Cleveland Lab
Classic Paper: Konopka and Benzer (1971) Clock mutants of Drosophila melanogaster. PNAS 68: 2112-2116. [PNAS] [PMC]

October 18: Spencer Goodman, Cherqui Lab
Curtis (2015) Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1. PNAS 112: 7231–7236. [PNAS] [PMC]

October 25: Samuel Lin, Wasserman Lab
He et al. (2009) The Transcriptional Repressor DEC2 Regulates Sleep Length in Mammals. Science 325: 866-870. [Science] [PMC]

November 1: Alannah Miranda, Kelsoe Lab
Zhang et al. (2016) A PERIOD3 variant causes a circadian phenotype and is associated with a seasonal mood trait. PNAS 113: E1536-44. [PNAS] [PMC]

November 8: Shanna Newton, Mellon Lab
Vitaterna et al. (1994) Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior. Science 264: 719-725. [Science] [PMC]

November 15: Alison Parisian, Furnari Lab
Etchegaray et al. (2003) Rhythmic histone acetylation underlies transcription in the mammalian circadian clock. Nature 421: 177-182. [Nature]

November 22: Thanksgiving Holiday

November 29: Brian Reilly, Bejar Lab
Terajima et al. (2017) ADARB1 catalyzes circadian A-to-I editing to regulate RNA rhythm. Nature Genetics 49: 146-151. [Nature Genetics]

December 6: Emily Wheeler, Yeo Lab
Perelis et al. (2015) Pancreatic b cell enhancers regulate rhythmic transcription of genes controlling insulin secretion. Science 350: aac4250. [Science] [PMC]

December 13: Responsible Conduct of Research
Timely public access to data from publicly funded research. Selection of Winter Topic.
Faculty panel

Winter 2018 - Preprints

January 10: Andrew Cooper, Schroeder Lab
Ruan et al (2017) A cassava drought inducible CC-type glutaredoxin, MeGRX232, negatively regulates drought tolerance in Arabidopsis by inhibition of ABA-dependent stomatal closure. bioRxiv April 12, 2017. [preprint]

January 17: Elie Farah, Chi Lab
Friedman et al. (2017) Cardiac directed differentiation using small molecule Wnt modulation at single-cell resolution. bioRxiv December 7, 2017. [preprint]

January 24: Responsible Conduct of Research
Human subjects in international collaborations. Prof. Joseph Gleeson.

January 31: Nina Gao, Nizet Lab
TBA.

February 7: Shereen Georges, Gleeson Lab
TBA.

February 14: Natalie Hollingsworth, Oegema Lab
TBA.

February 21: Ryan Marina, Yeo Lab
TBA.

February 28: Caroline Sferrazza, Goldstein Lab
TBA.

March 7: Mike Vaill, Varki Lab
TBA.

March 14: Mike Valdez, Farley Lab
TBA.